U.S. stock futures are pointing lower as investors watch for a potential partial government shutdown; economists expect the Personal Consumption Expenditures (PCE) index to show inflation moved higher in November; Novo Nordisk (NVO) stock is plummeting in premarket trading after disappointing data for its obesity shot CagriSema; FedEx (FDX) stock is jumping as the shipper proposed splitting off its freight unit; and Nike (NKE) shares are falling after the sneaker giant warned current-quarter reve𒁏nue could drop by more than 10%; Here's what🎃 investors need to know today.

1. US Stock Futures Lower 💖as Potential Government Shutdown Looms

U.S. stock futures are lower as markets brace for a potential partial government shutdown amid negotiations on a spending package in Washington. Nasdaq and 澳洲幸运5官方开奖结果体彩网:S&P 500 futures are down by 1.5% and 1.0%, respectively. After the 澳洲幸运5官方开奖结果体彩网:Dow Jones Industrial Average broke a 澳洲幸运5官方开奖结果体彩网:10-day losing streak Thursday, futures are 0.6% lower. Investors are also eyeing key inflation data that is set for release this morning. Bitcoin (BTCUSD) is more than 5% lower at around $92,000 and crude oil futures are༺ down about 1%. Gold futures are edging higher and yields on the 10-year Treasury note are edging lower, hovering above 4.5%.

2. Economists ꦺExpecting PCE Inflati𓂃on Reading to Rise

Investors are watching for the 8:30 a.m. ET release of the 澳洲幸运5官方开奖结果体彩网:Personal C🍃onsumption Eღxpenditures (PCE) index, which is 澳洲幸运5官方开奖结果体彩网:expected to show that inflation moved higher in November. Economists surveyed by The Wall Street Journal and Dow Jones Newswires expect the PCE to show that inflation rose 2.5% year-over-year in November, up from 2.3% in October. The trend would mirror a rise in price pressures recorded by 澳洲幸运5官方开奖结果体彩网:other inflation measurements and comes as the 澳洲幸运5官方开奖结果体彩网:Federal Reserve pulled back its 澳洲幸运5官方开奖结果体彩网:interest-rate outlook on worries that inflation may be stickier than previously thoug♚ht.

3. Novo Nordisk Sto💎ck Di𒉰ves on Weak Obesity Shot Data

U.S.-listed shares of Novo Nordisk (NVO), maker of popular weight-loss drugs 澳洲幸运5官方开奖结果体彩网:Ozempic and Wegovy, are plummeting 19% in premarket trading after tests showed its experimental obesity shot CagriSema was less effective than previously thought. Novo Nordisk said that the treatment produced a 22.7% weight loss in test patients after 68 weeks. That's less than the 25% weight loss that the Danish pharmaceutical company expected the drug to produce, Bloomberg reported. Shares of Eli Lilly (LLY), maker of ri🥂val drugs Zepbound and Mounjaro, are surging 5% ཧin response.

4. FedEx Stock Jumps on Plans to Spin Off F൩reight Business

FedEx (FDX) stock is surging 8% in premarket trading after the 澳洲幸运5官方开奖结果体彩网:shipping giant announced plans to spin off its Freight unit into a standalone company. FedEx said it would start the process immediately and it likely would take about 18 months. The company reported quarterly revenue of $21.97 billion, down from last year and below estimates. Profit fell to $741 milli🤡on from $900 million, also missing analysts' projections.

5. Nike Stock Dips on Revenue Warning

Nike (NKE) stock is 6% lower in premarket trading despite 澳洲幸运5官方开奖结果体彩网:reporting second-quarter results above estimates, as executives warned that they expect "Q3 revenues to be down low double-digits," according to a transcript of the earnings call provided by AlphaSense. The sneaker giant reported net income of $1.16 billion on revenue of $12.35 billion, above 澳洲幸运5官方开奖结果体彩网:analysts' estimates🍌 of $968 mill🍨ion in net income on revenue of $12.12 billion, according to Visible Alpha.