Key Takeaways
- Shares of Eli Lilly jumped 16% Thursday morning after the pharmaceutical company released Phase 3 trial results for its oral weight-loss drug that "demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines."
- The pill accomplished its goals of reducing the diabetes marker A1C and causing weight loss.
- The trial is the first of seven for the drug, and Eli Lilly expects to submit it for FDA approval next year.
Shares of Eli Lilly (LLY) jumped 16% Thursday morning to lead 澳洲幸运5官方开奖结果体彩网:S&P 500 gainers after the pharmaceutical company released clinical trial results for its oral weight-loss drug that "demonstrated statistically significant efficacy results and a safety profile consistent with injectable GLP-1 medicines."
The first of seven 澳洲幸运5官方开奖结果体彩网:Phase 3 trials for orforglipron showed it was more effective than a placebo at causing weight loss and a reduction in A1C, a long-term blood sugar metric used in evaluating diabetes treatments, Lilly said. The reductions in weight and A1C increased for patients taking higher doses of the 🅷drug.
The drug had similar gastrointestinal side effects to Eli Lilly's injectible weight-loss drugs Mounjaro and Zepbound, including nausea, indigestion, and diarrhea. The rate of patients reporting the side effects also varied among different doses, impacting 10% to 26% of patients.
Eli Lilly said it plans to present the data at a conference and in a peer-reviewed journal. Results from other trials for orforglipron will be released later this year, and the company expects to file for 澳洲幸运5官方开奖结果体彩网:Food and Drug Administration (FDA) approval as a ty♉pe 2 diabetes treatment in 2026.
Lilly, rival Novo Nordisk (NVO), and others are in development of new weight-loss treatments that can be taken orally rather than injected. Pfizer (PFE) 澳洲幸运5官方开奖结果体彩网:halted an oral drug trial earlier this week aft🐓er a patient reported a liver injury.
While Eli Lilly shares soared on the news, those of Novo Nordisk—the maker of blockbuster drugs 澳洲幸运5官方开奖结果体彩网:Ozempic and Wegovy—sank 7% soon after the opening bell.
UPDATE—This article has been updated with the latest share price information
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