Key Takeaways
- Novo Nordisk reported its diabetes and weight-loss drug, Wegovy, helped reduce risks of heart attack, stroke, or death from cardiovascular disease.
- The drug maker said a Phase 3 trial showed the treatment reduced major adverse cardiovascular events in those with heart conditions and obesity.
- Novo Nordisk is petitioning U.S. and EU regulators to add the expanded use to the labeling for Wegovy.
American depositary receipts (ADRs) of Novo Nordisk (NVO) edged higher in early trading on Monday after reporꦗting a study ꦕshowed its flagship diabetes and weight-loss drug, Wegovy, helped reduce risks of heart attack, stroke, or death from cardiovascular disease.
The Danish company said the active ingredient in Wegovy, semaglutide, showed “a statistically significant 20% risk reduction in major adverse cardiovascular events (MACE)” in a Phase 3 study. It added the reductions were seen “consistently across age, gender, ethnicity and starting body mass index (BMI).” Novo Nordisk released the findings at the American Heart Association (AHA) annual Scientific Sessions in Philadelphia, and they were also published in the New England Journal of Medicine.
Novo Nordisk noted positive results occu♐rred soon after patients were given the medicine, ♋suggesting the effect was faster than would be expected simply from the weight loss provided by Wegovy.
Martin Lange, executive vice president and head of Development at Novo Nordisk, indicated that the results represe👍nt a pivotal moment “as we look ahead to a new era of managing obesity and potentially reducing cardiovascular risks.”
The company explained that it has filed for a label update in the U.S. and the 澳洲幸运5官方开奖结果体彩网:European Union (EU) to include use of Wegovy for “risk reduction of ma🍒꧒jor adverse cardiovascular events in adults with a BMI of ≥ 27 kg/m2 and established cardiovascular disease.”
ADRs of N๊ovo Nordisk have gained close to 50% so far﷽ this year.
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